Quinidine and unidirectional cation fluxes in atria.
نویسندگان
چکیده
The effect of quinidine on unidirectional fluxes of Na and K in isolated rabbit atria has been investigated and correlated with known effects of the drug on the electrical and mechanical properties of the heart. Quinidine caused a rapid inhibition of J\a entry, which secondarily depressed K efflux. In addition, the drug depressed membrane permeability to K and caused a marked inhibition of active transport, both of which were relatively slow in onset.
منابع مشابه
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عنوان ژورنال:
- Circulation research
دوره 8 شماره
صفحات -
تاریخ انتشار 1960